MOBILITY & JOINTS

Adequan Canine Recall: What Dog Owners Need to Know

Last updated: August 17, 2026 · Written by Sam, Founder

Veterinarian checking the lot number on an Adequan Canine Injection vial

American Regent recalled two Adequan Canine lots after glass fibers were found in testing. Check your lot number and see what to do next.

American Regent recalled two lots of Adequan Canine Injection on July 31, 2026, after finding glass fibers in retained product samples. If your dog is on Adequan for arthritis, check the lot number on your vial — it’s lot 3369 or 25011 — and stop use immediately if it matches. No adverse events have been reported so far.

What was recalled, and why

American Regent, Inc. Animal Health issued a nationwide voluntary recall covering:

Adequan Canine Injection, 100 mg/mL, 5-mL multidose vials — Lot 3369 (distributed 5/22/2024, expires 10/31/2026) and Lot 25011 (distributed 4/14/2025, expires 12/31/2027)

A related recall also covers two lots of Adequan i.m., the equine version of the drug — that recall does not affect dogs and isn’t the focus here.

The company found glass fibers during routine testing of samples it had kept in storage. Adequan is injected intramuscularly, so particulate matter in the product is a real concern: injecting material like this can cause local irritation, swelling, inflammation, pain at the injection site, infection, or abscesses. As of the announcement, no adverse events tied to the recalled lots had been reported.

Why this matters more for senior dogs specifically

Adequan isn’t a typical pain reliever — it’s a disease-modifying osteoarthritis drug that works by slowing cartilage breakdown and supporting joint fluid over time. That’s exactly why it’s so commonly prescribed for older dogs with arthritis, especially ones who can’t tolerate long-term NSAID use. Many owners of senior dogs give maintenance doses at home after the first few injections are administered at the clinic — which means checking your own supply at home matters just as much as anything sitting in your vet’s fridge.

How to check if your dog’s Adequan is affected

Find any vials of Adequan Canine Injection you have at home or ask your vet to check what’s in their inventory.
Look at the lot number printed on the vial label.
Compare it against the two recalled lots: 3369 and 25011.
If it doesn’t match either number, the vial is not part of this recall.

What to do if your vial matches a recalled lot

Stop using it immediately. Don’t administer any remaining doses.
Contact your veterinarian before your next scheduled injection.
Return or dispose of the vial according to your vet’s or the manufacturer’s instructions — don’t just throw it in household trash.
Watch your dog for unusual swelling, pain, warmth, or discharge at a recent injection site, and call your vet if you notice anything.

If your dog already received a dose from a recalled lot before this recall was announced, that alone isn’t a reason to panic — no adverse events have been reported to date. It’s still worth mentioning at your next vet visit so it’s noted in their record.

The bottom line

This recall is precautionary, based on a manufacturing finding rather than a confirmed pattern of harm. But because Adequan is injected rather than eaten, and because so many senior dogs are on it long-term, a five-minute lot-number check is worth doing today rather than waiting for your next refill.

This article is for informational purposes only and does not replace guidance from your veterinarian.

FAQ

What is Adequan Canine Injection used for?

Adequan Canine is an FDA-approved prescription injection used to manage noninfectious degenerative or traumatic arthritis in dogs. Unlike a painkiller, it works by slowing cartilage breakdown and supporting joint fluid, which is why vets often choose it for dogs who can't tolerate long-term NSAID use.

Which Adequan lots are affected by the recall?

The recall covers Adequan Canine Injection (100 mg/mL, 5-mL multidose vials) lot numbers 3369 and 25011. A separate but related recall covers two lots of Adequan i.m., the equine version, which does not affect dogs.

Why was Adequan Canine recalled?

American Regent found glass fibers during testing of internally retained product samples. Injecting a product containing particulate matter can cause local irritation, swelling, inflammation, pain at the injection site, infection, or abscesses.

Has anyone reported a reaction to the recalled lots?

As of the July 31, 2026 announcement, American Regent had not received any reports of adverse events linked to the recalled lots. The recall was issued as a precaution based on the manufacturing finding, not confirmed harm.

What should I do if my dog's vial matches a recalled lot number?

Stop using it immediately and contact your veterinarian. Do not administer any remaining doses from that vial, and follow your vet's or the manufacturer's instructions for returning or disposing of it.

My dog already received a dose before I saw this — what now?

Watch the injection site for unusual swelling, pain, warmth, or discharge over the following days, and contact your vet if you notice anything abnormal or if your dog seems unwell. No adverse events have been reported so far, but it's worth mentioning the recall to your vet at your next visit regardless.